Please use this identifier to cite or link to this item:
https://hdl.handle.net/10316/101257
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Santos-Ferreira, Cátia A. | - |
dc.contributor.author | Abreu, Mónica T. | - |
dc.contributor.author | Marques, Carla I. | - |
dc.contributor.author | Gonçalves, Lino M. | - |
dc.contributor.author | Baptista, Rui | - |
dc.contributor.author | Girão, Henrique M. | - |
dc.date.accessioned | 2022-08-18T09:17:54Z | - |
dc.date.available | 2022-08-18T09:17:54Z | - |
dc.date.issued | 2020-11 | - |
dc.identifier.issn | 2452302X | - |
dc.identifier.uri | https://hdl.handle.net/10316/101257 | - |
dc.description.abstract | Pulmonary arterial hypertension (PAH) is a rare, chronic disease of the pulmonary vasculature that is associated with poor outcomes. Its pathogenesis is multifactorial and includes micro-RNA (miRNA) deregulation. The understanding of the role of miRNAs in PAH is expanding quickly, and it is increasingly difficult to identify which miRNAs have the highest translational potential. This review summarizes the current knowledge of miRNA expression in PAH, discusses the challenges in miRNA analysis and interpretation, and highlights 4 promising miRNAs in this field (miR-29, miR-124, miR-140, and miR-204). | pt |
dc.language.iso | eng | pt |
dc.relation | POCI-01-0145-FEDER-032414 | pt |
dc.relation | POCI-01-0145-FEDER-016385 | pt |
dc.relation | CENTRO-01-0145-FEDER-000012-N2323 | pt |
dc.relation | POCI-01-0145-FEDER-007440 | pt |
dc.relation | CENTRO-01-0145-FEDER-032179 | pt |
dc.relation | POCI-01-0145-FEDER-022122, | pt |
dc.relation | UID/NEU/04539/2019 | pt |
dc.relation | UIDB/04539/2020 | pt |
dc.relation | UIDP/04539/2020 | pt |
dc.rights | openAccess | pt |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | pt |
dc.subject | animal model | pt |
dc.subject | micro-RNA | pt |
dc.subject | microarray | pt |
dc.subject | pulmonary arterial hypertension | pt |
dc.title | Micro-RNA Analysis in Pulmonary Arterial Hypertension: Current Knowledge and Challenges | pt |
dc.type | article | pt |
degois.publication.firstPage | 1149 | pt |
degois.publication.lastPage | 1162 | pt |
degois.publication.issue | 11 | pt |
degois.publication.title | JACC: Basic to Translational Science | pt |
dc.peerreviewed | yes | pt |
dc.identifier.doi | 33294743 | - |
dc.identifier.doi | 2452-302X | - |
dc.identifier.doi | 33294743 | - |
dc.identifier.doi | 2452-302X | - |
dc.identifier.doi | 33294743 | - |
dc.identifier.doi | 2452-302X | - |
dc.identifier.doi | 33294743 | - |
dc.identifier.doi | 2452-302X | - |
dc.identifier.doi | 2452-302X | - |
dc.identifier.doi | 33294743 | - |
dc.identifier.doi | 10.1016/j.jacbts.2020.07.008 | - |
dc.identifier.doi | 33294743 | - |
dc.identifier.doi | 2452-302X | - |
dc.identifier.doi | 33294743 | - |
dc.identifier.doi | 2452-302X | - |
dc.identifier.doi | 33294743 | - |
dc.identifier.doi | 2452-302X | - |
degois.publication.volume | 5 | pt |
dc.date.embargo | 2020-11-01 | * |
dc.identifier.pmid | 33294743 | - |
uc.date.periodoEmbargo | 0 | pt |
dc.identifier.eissn | 2452-302X | - |
item.fulltext | Com Texto completo | - |
item.grantfulltext | open | - |
item.languageiso639-1 | en | - |
item.cerifentitytype | Publications | - |
item.openairetype | article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
crisitem.project.grantno | CNC. IBILI | - |
crisitem.project.grantno | Center for Innovative Biomedicine and Biotechnology - CIBB | - |
crisitem.project.grantno | Center for Innovative Biomedicine and Biotechnology | - |
crisitem.author.researchunit | ICBR Coimbra Institute for Clinical and Biomedical Research | - |
crisitem.author.researchunit | CNC - Center for Neuroscience and Cell Biology | - |
crisitem.author.researchunit | CNC - Center for Neuroscience and Cell Biology | - |
crisitem.author.researchunit | CNC - Center for Neuroscience and Cell Biology | - |
crisitem.author.parentresearchunit | Faculty of Medicine | - |
crisitem.author.orcid | 0000-0002-1817-4813 | - |
crisitem.author.orcid | 0000-0001-9255-3064 | - |
crisitem.author.orcid | 0000-0002-7411-7039 | - |
crisitem.author.orcid | 0000-0002-5786-8447 | - |
Appears in Collections: | I&D ICBR - Artigos em Revistas Internacionais I&D CIBB - Artigos em Revistas Internacionais |
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File | Description | Size | Format | |
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1-s2.0-S2452302X20303405-main.pdf | 1.57 MB | Adobe PDF | View/Open |
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