Please use this identifier to cite or link to this item: https://hdl.handle.net/10316/101257
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dc.contributor.authorSantos-Ferreira, Cátia A.-
dc.contributor.authorAbreu, Mónica T.-
dc.contributor.authorMarques, Carla I.-
dc.contributor.authorGonçalves, Lino M.-
dc.contributor.authorBaptista, Rui-
dc.contributor.authorGirão, Henrique M.-
dc.date.accessioned2022-08-18T09:17:54Z-
dc.date.available2022-08-18T09:17:54Z-
dc.date.issued2020-11-
dc.identifier.issn2452302X-
dc.identifier.urihttps://hdl.handle.net/10316/101257-
dc.description.abstractPulmonary arterial hypertension (PAH) is a rare, chronic disease of the pulmonary vasculature that is associated with poor outcomes. Its pathogenesis is multifactorial and includes micro-RNA (miRNA) deregulation. The understanding of the role of miRNAs in PAH is expanding quickly, and it is increasingly difficult to identify which miRNAs have the highest translational potential. This review summarizes the current knowledge of miRNA expression in PAH, discusses the challenges in miRNA analysis and interpretation, and highlights 4 promising miRNAs in this field (miR-29, miR-124, miR-140, and miR-204).pt
dc.language.isoengpt
dc.relationPOCI-01-0145-FEDER-032414pt
dc.relationPOCI-01-0145-FEDER-016385pt
dc.relationCENTRO-01-0145-FEDER-000012-N2323pt
dc.relationPOCI-01-0145-FEDER-007440pt
dc.relationCENTRO-01-0145-FEDER-032179pt
dc.relationPOCI-01-0145-FEDER-022122,pt
dc.relationUID/NEU/04539/2019pt
dc.relationUIDB/04539/2020pt
dc.relationUIDP/04539/2020pt
dc.rightsopenAccesspt
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt
dc.subjectanimal modelpt
dc.subjectmicro-RNApt
dc.subjectmicroarraypt
dc.subjectpulmonary arterial hypertensionpt
dc.titleMicro-RNA Analysis in Pulmonary Arterial Hypertension: Current Knowledge and Challengespt
dc.typearticlept
degois.publication.firstPage1149pt
degois.publication.lastPage1162pt
degois.publication.issue11pt
degois.publication.titleJACC: Basic to Translational Sciencept
dc.peerreviewedyespt
dc.identifier.doi33294743-
dc.identifier.doi2452-302X-
dc.identifier.doi33294743-
dc.identifier.doi2452-302X-
dc.identifier.doi33294743-
dc.identifier.doi2452-302X-
dc.identifier.doi33294743-
dc.identifier.doi2452-302X-
dc.identifier.doi2452-302X-
dc.identifier.doi33294743-
dc.identifier.doi10.1016/j.jacbts.2020.07.008-
dc.identifier.doi33294743-
dc.identifier.doi2452-302X-
dc.identifier.doi33294743-
dc.identifier.doi2452-302X-
dc.identifier.doi33294743-
dc.identifier.doi2452-302X-
degois.publication.volume5pt
dc.date.embargo2020-11-01*
dc.identifier.pmid33294743-
uc.date.periodoEmbargo0pt
dc.identifier.eissn2452-302X-
item.fulltextCom Texto completo-
item.grantfulltextopen-
item.languageiso639-1en-
item.cerifentitytypePublications-
item.openairetypearticle-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
crisitem.project.grantnoCNC. IBILI-
crisitem.project.grantnoCenter for Innovative Biomedicine and Biotechnology - CIBB-
crisitem.project.grantnoCenter for Innovative Biomedicine and Biotechnology-
crisitem.author.researchunitICBR Coimbra Institute for Clinical and Biomedical Research-
crisitem.author.researchunitCNC - Center for Neuroscience and Cell Biology-
crisitem.author.researchunitCNC - Center for Neuroscience and Cell Biology-
crisitem.author.researchunitCNC - Center for Neuroscience and Cell Biology-
crisitem.author.parentresearchunitFaculty of Medicine-
crisitem.author.orcid0000-0002-1817-4813-
crisitem.author.orcid0000-0001-9255-3064-
crisitem.author.orcid0000-0002-7411-7039-
crisitem.author.orcid0000-0002-5786-8447-
Appears in Collections:I&D ICBR - Artigos em Revistas Internacionais
I&D CIBB - Artigos em Revistas Internacionais
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