Utilize este identificador para referenciar este registo:
https://hdl.handle.net/10316/103384
Campo DC | Valor | Idioma |
---|---|---|
dc.contributor.author | Fernandes, Iva | - |
dc.contributor.author | Oliveira, Joana | - |
dc.contributor.author | Pinho, Aryane | - |
dc.contributor.author | Carvalho, Eugenia | - |
dc.date.accessioned | 2022-11-09T13:03:59Z | - |
dc.date.available | 2022-11-09T13:03:59Z | - |
dc.date.issued | 2022-02-17 | - |
dc.identifier.issn | 2218-1989 | pt |
dc.identifier.uri | https://hdl.handle.net/10316/103384 | - |
dc.description.abstract | Research in pharmacological therapy has led to the availability of many antidiabetic agents. New recommendations for precision medicine and particularly precision nutrition may greatly contribute to the control and especially to the prevention of diabetes. This scenario greatly encourages the search for novel non-pharmaceutical molecules. In line with this, the daily and long-term consumption of diets rich in phenolic compounds, together with a healthy lifestyle, may have a protective role against the development of type 2 diabetes. In the framework of the described studies, there is clear evidence that the bio accessibility, bioavailability, and the gut microbiota are indeed affected by: the way phenolic compounds are consumed (acutely or chronically; as pure compounds, extracts, or in-side a whole meal) and the amount and the type of phenolic compounds (ex-tractable or non-extractable/macromolecular antioxidants, including non-bioavailable polyphenols and plant matrix complexed structures). In this review, we report possible effects of important, commonly consumed, phenolic-based nutraceuticals in pre-clinical and clinical diabetes studies. We highlight their mechanisms of action and their potential effects in health promotion. Translation of this nutraceutical-based approach still requires more and larger clinical trials for better elucidation of the mechanism of action toward clinical applications. | pt |
dc.description.sponsorship | AgriFood XXI I&D&I project (NORTE- 01-0145-FEDER-000041, cofinanced by the European Regional Development Fund (ERDF), through NORTE 2020 (Programa Operacional Regional do Norte 2014/2020) | pt |
dc.language.iso | eng | pt |
dc.relation | UIDB/04539/2020 | pt |
dc.relation | UIDB/50006/2020 | pt |
dc.relation | UIDP/50006/2020 | pt |
dc.relation | CENTRO-01-0145-FEDER-000012/HealthyAging2020 | pt |
dc.relation | info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UID/NEU/04539/2013/PT | pt |
dc.rights | openAccess | pt |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | pt |
dc.subject | diabetes | pt |
dc.subject | glucose | pt |
dc.subject | insulin resistance | pt |
dc.subject | nutraceuticals | pt |
dc.subject | polyphenols | pt |
dc.subject | whole food | pt |
dc.title | The Role of Nutraceutical Containing Polyphenols in Diabetes Prevention | pt |
dc.type | article | - |
degois.publication.firstPage | 184 | pt |
degois.publication.issue | 2 | pt |
degois.publication.title | Metabolites | pt |
dc.peerreviewed | yes | pt |
dc.identifier.doi | 10.3390/metabo12020184 | pt |
degois.publication.volume | 12 | pt |
dc.date.embargo | 2022-02-17 | * |
uc.date.periodoEmbargo | 0 | pt |
item.fulltext | Com Texto completo | - |
item.grantfulltext | open | - |
item.languageiso639-1 | en | - |
item.cerifentitytype | Publications | - |
item.openairetype | article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
crisitem.project.grantno | Center for Innovative Biomedicine and Biotechnology - CIBB | - |
crisitem.project.grantno | Associated Laboratory for Green Chemistry - Clean Technologies and Processes- REQUIMTE | - |
crisitem.project.grantno | Associated Laboratory for Green Chemistry - Clean Technologies and Processes | - |
crisitem.project.grantno | CNC. IBILI | - |
crisitem.author.orcid | 0000-0003-2235-2237 | - |
crisitem.author.orcid | 0000-0001-6264-3632 | - |
Aparece nas coleções: | I&D CNC - Artigos em Revistas Internacionais FCTUC Ciências da Vida - Artigos em Revistas Internacionais IIIUC - Artigos em Revistas Internacionais |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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The-Role-of-Nutraceutical-Containing-Polyphenols-in-Diabetes-PreventionMetabolites.pdf | 2.59 MB | Adobe PDF | Ver/Abrir |
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