Please use this identifier to cite or link to this item: https://hdl.handle.net/10316/105854
Title: Germline Genetic Variants of the Renin-Angiotensin System, Hypoxia and Angiogenesis in Non-Small Cell Lung Cancer Progression: Discovery and Validation Studies
Authors: Catarata, Maria Joana
Medeiros, Rui 
Oliveira, Maria José 
Pêgo, Alice 
Frade, João Gonçalo 
Martins, Maria de Fátima 
Cordeiro, Carlos Robalo 
Herth, Felix J. F.
Thomas, Michael
Kriegsmann, Mark
Meister, Michael
Schneider, Marc A
Muley, Thomas
Ribeiro, Ricardo
Keywords: genetic polymorphisms; lung cancer; renin–angiotensin; hypoxia; angiogenesis
Issue Date: 18-Dec-2020
Publisher: MDPI
Project: Associação de Estudos Respiratórios and the Portuguese Pulmonology Society 
Serial title, monograph or event: Cancers
Volume: 12
Issue: 12
Abstract: The renin-angiotensin system (RAS) is involved in cell proliferation, immunoinflammatory response, hypoxia and angiogenesis, which are critical biological processes in lung cancer. Our aim was to study the association of putatively functional genetic polymorphisms in genes coding for proteins involved in RAS, hypoxia and angiogenesis with non-small cell lung cancer (NSCLC) prognosis.
URI: https://hdl.handle.net/10316/105854
ISSN: 2072-6694
DOI: 10.3390/cancers12123834
Rights: openAccess
Appears in Collections:FMUC Medicina - Artigos em Revistas Internacionais

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