Please use this identifier to cite or link to this item:
https://hdl.handle.net/10316/107302
Title: | Viable Neisseria meningitidis is commonly present in saliva in healthy young adults: Non-invasive sampling and enhanced sensitivity of detection in a follow-up carriage study in Portuguese students | Authors: | Rodrigues, Fernanda Christensen, Hannah Morales-Aza, Begonia Sikora, Paulina Oliver, Elizabeth Oliver, Jennifer Lucidarme, Jay Marlow, Robin Januário, Luís Finn, Adam |
Issue Date: | 2019 | Publisher: | Public Library of Science | Project: | Pfizer National Institute for Health Research Health Protection Research Unit (NIHR HPRU) in Evaluation of Interventions at the University of Bristol in partnership with Public Health England |
Serial title, monograph or event: | PLoS ONE | Volume: | 14 | Issue: | 2 | Abstract: | Improved sensitivity and efficiency of detection and quantification of carriage of Neisseria meningitidis (Nm) in young people is important for evaluation of the impact of vaccines upon transmission and associated population-wide effects. Saliva collection is quick, non-invasive and facilitates frequent sampling, but has been reported to yield low sensitivity by culture. We re-evaluated this approach in a follow-up cross sectional study using direct and culture-amplified PCR. | URI: | https://hdl.handle.net/10316/107302 | ISSN: | 1932-6203 | DOI: | 10.1371/journal.pone.0209905 | Rights: | openAccess |
Appears in Collections: | FMUC Medicina - Artigos em Revistas Internacionais |
Files in This Item:
This item is licensed under a Creative Commons License