Please use this identifier to cite or link to this item:
https://hdl.handle.net/10316/107427
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Correia-Barros, Gabriela | - |
dc.contributor.author | Serambeque, Beatriz | - |
dc.contributor.author | Carvalho, Maria João | - |
dc.contributor.author | Marto, Carlos Miguel | - |
dc.contributor.author | Pineiro, Marta | - |
dc.contributor.author | Pinho e Melo, Teresa M. V. D. | - |
dc.contributor.author | Botelho, M. Filomena | - |
dc.contributor.author | Laranjo, Mafalda | - |
dc.date.accessioned | 2023-07-11T08:56:46Z | - |
dc.date.available | 2023-07-11T08:56:46Z | - |
dc.date.issued | 2022-05-23 | - |
dc.identifier.issn | 2306-5354 | pt |
dc.identifier.uri | https://hdl.handle.net/10316/107427 | - |
dc.description.abstract | Photodynamic therapy (PDT) is a medical procedure useful for several benign conditions (such as wound healing and infections) and cancer. PDT is minimally invasive, presents few side effects, good scaring, and is able to minimal tissue destruction maintaining organ anatomy and function. Endoscopic access to the uterus puts PDT in the spotlight for endometrial disease treatment. This work systematically reviews the current evidence of PDT's potential and usefulness in endometrial diseases. Thus, this narrative review focused on PDT applications for endometrial disease, including reports regarding in vitro, ex vivo, animal, and clinical studies. Cell lines and primary samples were used as in vitro models of cancer, adenomyosis and endometrioses, while most animal studies focused the PDT outcomes on endometrial ablation. A few clinical attempts are known using PDT for endometrial ablation and cancer lesions. This review emphasises PDT as a promising field of research. This therapeutic approach has the potential to become an effective conservative treatment method for endometrial benign and malignant lesions. Further investigations with improved photosensitisers are highly expected. | pt |
dc.language.iso | eng | pt |
dc.publisher | MDPI | pt |
dc.relation | 2020.07672.BD | pt |
dc.relation | PTDC/QUI-QOR/0103/2021 | pt |
dc.relation | UID/NEU/04539/2019 | pt |
dc.relation | info:eu-repo/grantAgreement/UIDP/04539/2020 | pt |
dc.relation | UIDB/04539/2020 | pt |
dc.relation | UIDB/00313/2020 | pt |
dc.relation | UIDP/00313/2020 | pt |
dc.rights | openAccess | pt |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | pt |
dc.subject | endometrial neoplasms | pt |
dc.subject | endometrium | pt |
dc.subject | models | pt |
dc.subject | animal | pt |
dc.subject | photochemotherapy | pt |
dc.subject | photodynamic therapy | pt |
dc.subject | therapeutics | pt |
dc.title | Applications of Photodynamic Therapy in Endometrial Diseases | pt |
dc.type | article | - |
degois.publication.firstPage | 226 | pt |
degois.publication.issue | 5 | pt |
degois.publication.title | Bioengineering | pt |
dc.peerreviewed | yes | pt |
dc.identifier.doi | 10.3390/bioengineering9050226 | pt |
degois.publication.volume | 9 | pt |
dc.date.embargo | 2022-05-23 | * |
uc.date.periodoEmbargo | 0 | pt |
item.fulltext | Com Texto completo | - |
item.grantfulltext | open | - |
item.languageiso639-1 | en | - |
item.cerifentitytype | Publications | - |
item.openairetype | article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
crisitem.project.grantno | CNC. IBILI | - |
crisitem.project.grantno | Center for Innovative Biomedicine and Biotechnology | - |
crisitem.project.grantno | Center for Innovative Biomedicine and Biotechnology - CIBB | - |
crisitem.project.grantno | Coimbra Chemistry Center | - |
crisitem.project.grantno | Coimbra Chemistry Center | - |
crisitem.author.researchunit | ICBR Coimbra Institute for Clinical and Biomedical Research | - |
crisitem.author.researchunit | CQC - Coimbra Chemistry Centre | - |
crisitem.author.researchunit | CQC - Coimbra Chemistry Centre | - |
crisitem.author.researchunit | CNC - Center for Neuroscience and Cell Biology | - |
crisitem.author.parentresearchunit | Faculty of Medicine | - |
crisitem.author.parentresearchunit | Faculty of Sciences and Technology | - |
crisitem.author.parentresearchunit | Faculty of Sciences and Technology | - |
crisitem.author.orcid | 0000-0001-9269-5417 | - |
crisitem.author.orcid | 0000-0002-7460-3758 | - |
crisitem.author.orcid | 0000-0003-3256-4954 | - |
crisitem.author.orcid | 0000-0001-7202-1650 | - |
crisitem.author.orcid | 0000-0003-0689-6007 | - |
Appears in Collections: | I&D CQC - Artigos em Revistas Internacionais I&D ICBR - Artigos em Revistas Internacionais I&D CIBB - Artigos em Revistas Internacionais FMUC Medicina - Artigos em Revistas Internacionais |
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File | Description | Size | Format | |
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CorreiaBarros2022Bioengineering.pdf | 729.99 kB | Adobe PDF | View/Open |
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