Please use this identifier to cite or link to this item:
https://hdl.handle.net/10316/108374
DC Field | Value | Language |
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dc.contributor.author | Ribeiro, Fernando | - |
dc.contributor.author | Ribeiro, Ilda P. | - |
dc.contributor.author | Gonçalves, Ana C. | - |
dc.contributor.author | Alves, Alberto J. | - |
dc.contributor.author | Melo, Elsa | - |
dc.contributor.author | Fernandes, Raquel | - |
dc.contributor.author | Costa, Rui | - |
dc.contributor.author | Ribeiro, Ana B. Sarmento | - |
dc.contributor.author | Duarte, José A. | - |
dc.contributor.author | Carreira, Isabel M. | - |
dc.contributor.author | Witkowski, Sarah | - |
dc.contributor.author | Oliveira, José | - |
dc.date.accessioned | 2023-08-28T08:08:22Z | - |
dc.date.available | 2023-08-28T08:08:22Z | - |
dc.date.issued | 2017-12-19 | - |
dc.identifier.issn | 2045-2322 | pt |
dc.identifier.uri | https://hdl.handle.net/10316/108374 | - |
dc.description.abstract | This study aimed to determine the effect of a single bout of resistance exercise at different intensities on the mobilization of circulating EPCs over 24 hours in women. In addition, the angiogenic factors stromal cell-derived factor 1 (SDF-1α), vascular endothelial growth factor (VEGF), hypoxia-inducible factor 1-alpha (HIF-1α) and erythropoietin (EPO) were measured as potential mechanisms for exercise-induced EPCs mobilization. Thirty-eight women performed a resistance exercise session at an intensity of 60% (n = 13), 70% (n = 12) or 80% (n = 13) of one repetition maximum. Each session was comprised of three sets of 12 repetitions of four exercises: bench press, dumbbell curl, dumbbell squat, and standing dumbbell upright row. Blood was sampled at baseline and immediately, 6 hours, and 24 hours post-exercise. Circulating EPC and levels of VEGF, HIF-1α and EPO were significantly higher after exercise (P < 0.05). The change in EPCs from baseline was greatest in the 80% group (P < 0.05), reaching the highest at 6 hours post-exercise. The change in EPCs from baseline to 6 hours post-exercise was correlated with the change in VEGF (r = 0.492, P = 0.002) and HIF-1α (r = 0.388, P = 0.016). In general, a dose-response relationship was observed, with the highest exercise intensities promoting the highest increases in EPCs and angiogenic factors. | pt |
dc.language.iso | eng | pt |
dc.publisher | Springer Nature | pt |
dc.relation | UID/BIM/04501/2013 | pt |
dc.relation | UID/ DTP/04045/2013 | pt |
dc.relation | POCI-01-0145- FEDER-006969 | pt |
dc.relation | FCOMP-01-0124-FEDER- 020180 (PTDC/ DES/122763/2010) and UID/DTP/00617/2013 | pt |
dc.rights | openAccess | pt |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | pt |
dc.subject.mesh | Adult | pt |
dc.subject.mesh | Endothelial Progenitor Cells | pt |
dc.subject.mesh | Erythropoietin | pt |
dc.subject.mesh | Exercise | pt |
dc.subject.mesh | Female | pt |
dc.subject.mesh | Humans | pt |
dc.subject.mesh | Hypoxia-Inducible Factor 1, alpha Subunit | pt |
dc.subject.mesh | Resistance Training | pt |
dc.subject.mesh | Vascular Endothelial Growth Factors | pt |
dc.subject.mesh | Young Adult | pt |
dc.title | Effects of resistance exercise on endothelial progenitor cell mobilization in women | pt |
dc.type | article | - |
degois.publication.firstPage | 17880 | pt |
degois.publication.issue | 1 | pt |
degois.publication.title | Scientific Reports | pt |
dc.peerreviewed | yes | pt |
dc.identifier.doi | 10.1038/s41598-017-18156-6 | pt |
degois.publication.volume | 7 | pt |
dc.date.embargo | 2017-12-19 | * |
uc.date.periodoEmbargo | 0 | pt |
item.openairetype | article | - |
item.cerifentitytype | Publications | - |
item.languageiso639-1 | en | - |
item.fulltext | Com Texto completo | - |
item.grantfulltext | open | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
crisitem.author.researchunit | ICBR Coimbra Institute for Clinical and Biomedical Research | - |
crisitem.author.researchunit | CNC - Center for Neuroscience and Cell Biology | - |
crisitem.author.researchunit | CNC - Center for Neuroscience and Cell Biology | - |
crisitem.author.parentresearchunit | Faculty of Medicine | - |
crisitem.author.orcid | 0000-0002-6096-8705 | - |
crisitem.author.orcid | 0000-0003-1470-4802 | - |
crisitem.author.orcid | 0000-0002-4142-4841 | - |
crisitem.author.orcid | 0000-0001-6842-1707 | - |
Appears in Collections: | I&D IBILI - Artigos em Revistas Internacionais I&D CNC - Artigos em Revistas Internacionais FMUC Medicina - Artigos em Revistas Internacionais |
Files in This Item:
File | Description | Size | Format | |
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Effects-of-resistance-exercise-on-endothelial-progenitor-cell-mobilization-in-womenScientific-Reports.pdf | 2.02 MB | Adobe PDF | View/Open |
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