Please use this identifier to cite or link to this item:
https://hdl.handle.net/10316/113439
DC Field | Value | Language |
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dc.contributor.author | Oliveira, Cátia S. D. | - |
dc.contributor.author | Moreira, Patrícia | - |
dc.contributor.author | Cruz, Maria T. | - |
dc.contributor.author | Pereira, Cláudia M. F. | - |
dc.contributor.author | Silva, Artur M. S. | - |
dc.contributor.author | Santos, Sónia A. O. | - |
dc.contributor.author | Silvestre, Armando J. D. | - |
dc.date.accessioned | 2024-02-20T10:25:41Z | - |
dc.date.available | 2024-02-20T10:25:41Z | - |
dc.date.issued | 2023-03-25 | - |
dc.identifier.issn | 1422-0067 | pt |
dc.identifier.uri | https://hdl.handle.net/10316/113439 | - |
dc.description.abstract | E. globulus leaves have been mainly exploited for essential oil recovery or for energy generation in industrial pulp mills, neglecting the abundance of valuable families of extractives, namely, triterpenic acids, that might open new ways for the integrated valorization of this biomass. Therefore, this study highlights the lipophilic characterization of E. globulus leaves before and after hydrodistillation, aiming at the integrated valorization of both essential oils and triterpenic acids. The lipophilic composition of E. globulus leaves after hydrodistillation is reported for the first time. Extracts were obtained by dichloromethane Soxhlet extraction and analyzed by gas chromatography-mass spectrometry. In addition, their cytotoxicity on different cell lines representative of the innate immune system, skin, liver, and intestine were evaluated. Triterpenic acids, such as betulonic, oleanolic, betulinic and ursolic acids, were found to be the main components of these lipophilic extracts, ranging from 30.63-37.14 g kg-1 of dry weight (dw), and representing 87.7-89.0% w/w of the total content of the identified compounds. In particular, ursolic acid was the major constituent of all extracts, representing 46.8-50.7% w/w of the total content of the identified compounds. Other constituents, such as fatty acids, long-chain aliphatic alcohols and β-sitosterol were also found in smaller amounts in the studied extracts. This study also demonstrates that the hydrodistillation process does not affect the recovery of compounds of greatest interest, namely, triterpenic acids. Therefore, the results establish that this biomass residue can be considered as a promising source of value-added bioactive compounds, opening new strategies for upgrading pulp industry residues within an integrated biorefinery context. | pt |
dc.language.iso | eng | pt |
dc.publisher | MDPI | pt |
dc.relation | POCI-01-0247-FEDER-021874 | pt |
dc.relation | UIDB/50011/2020 | pt |
dc.relation | UIDP/50011/2020 | pt |
dc.relation | LA/P/0006/2020 | pt |
dc.relation | UIDB/50006/2020 | pt |
dc.relation | UIDP/50006/2020 | pt |
dc.relation | UIDB/04539/2020 | pt |
dc.relation | 2021.03348.CEECIND | pt |
dc.relation | info:eu-repo/grantAgreement/UIDP/04539/2020 | pt |
dc.rights | openAccess | pt |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | pt |
dc.subject | Eucalyptus globulus leaves | pt |
dc.subject | biorefinery | pt |
dc.subject | integrated exploitation | pt |
dc.subject | hydrodistillation | pt |
dc.subject | GC–MS analysis | pt |
dc.subject | cytotoxicity | pt |
dc.subject | triterpenic acids | pt |
dc.subject | ursolic acid | pt |
dc.subject.mesh | Fatty Acids | pt |
dc.subject.mesh | Plant Extracts | pt |
dc.subject.mesh | Alcohols | pt |
dc.subject.mesh | Eucalyptus | pt |
dc.subject.mesh | Oils, Volatile | pt |
dc.subject.mesh | Triterpenes | pt |
dc.title | Exploiting the Integrated Valorization of Eucalyptus globulus Leaves: Chemical Composition and Biological Potential of the Lipophilic Fraction before and after Hydrodistillation | pt |
dc.type | article | - |
degois.publication.firstPage | 6226 | pt |
degois.publication.issue | 7 | pt |
degois.publication.title | International Journal of Molecular Sciences | pt |
dc.peerreviewed | yes | pt |
dc.identifier.doi | 10.3390/ijms24076226 | pt |
degois.publication.volume | 24 | pt |
dc.date.embargo | 2023-03-25 | * |
uc.date.periodoEmbargo | 0 | pt |
item.openairetype | article | - |
item.cerifentitytype | Publications | - |
item.languageiso639-1 | en | - |
item.fulltext | Com Texto completo | - |
item.grantfulltext | open | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
crisitem.author.researchunit | CNC - Center for Neuroscience and Cell Biology | - |
crisitem.author.researchunit | CNC - Center for Neuroscience and Cell Biology | - |
crisitem.author.researchunit | CNC - Center for Neuroscience and Cell Biology | - |
crisitem.author.orcid | 0000-0003-2727-512X | - |
crisitem.author.orcid | 0000-0001-9846-6754 | - |
crisitem.author.orcid | 0000-0002-6630-5056 | - |
crisitem.project.grantno | CICECO-Aveiro Institute of Materials | - |
crisitem.project.grantno | CICECO-Aveiro Institute of Materials | - |
crisitem.project.grantno | Associated Laboratory for Green Chemistry - Clean Technologies and Processes- REQUIMTE | - |
crisitem.project.grantno | Center for Innovative Biomedicine and Biotechnology - CIBB | - |
crisitem.project.grantno | Center for Innovative Biomedicine and Biotechnology | - |
Appears in Collections: | FMUC Medicina - Artigos em Revistas Internacionais FFUC- Artigos em Revistas Internacionais I&D CNC - Artigos em Revistas Internacionais |
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