Utilize este identificador para referenciar este registo: https://hdl.handle.net/10316/45373
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dc.contributor.authorFerreira, José Augusto-
dc.contributor.authorGonçalves, Lino-
dc.contributor.authorNaghipoor, Jahed-
dc.contributor.authorOliveira, Paula de-
dc.contributor.authorRabczuk, Timon-
dc.date.accessioned2017-12-21T14:35:45Z-
dc.date.issued2017-
dc.identifier.urihttps://hdl.handle.net/10316/45373-
dc.description.abstractIn this paper the effect of plaque composition, on the accumulation of drug released by a drug eluting stent, is analyzed. The mathematical model is represented by two coupled systems of partial differential equations that describe the pharmacokinetics of drug in the stent coating and in the arterial wall. The influence of the stiffness and porosity of soft and hard plaques is studied. A case study based on optical coherence tomography images is also included.por
dc.language.isoengpor
dc.publisherElsevierpor
dc.relationinfo:eu-repo/grantAgreement/FCT/5876/147205/PTpor
dc.rightsembargoedAccess-
dc.subjectAbsorbable Implantspor
dc.subjectAntineoplastic Agentspor
dc.subjectArteriespor
dc.subjectPaclitaxelpor
dc.subjectPlaque, Atheroscleroticpor
dc.subjectSirolimuspor
dc.subjectDrug-Eluting Stentspor
dc.subjectModels, Theoreticalpor
dc.titleThe influence of atherosclerotic plaques on the pharmacokinetics of a drug eluted from bioabsorbable stentspor
dc.typearticle-
degois.publication.firstPage71por
degois.publication.lastPage83por
degois.publication.titleMathematical Biosciencespor
dc.relation.publisherversionhttps://doi.org/10.1016/j.mbs.2016.11.005por
dc.peerreviewedyespor
dc.identifier.doi10.1016/j.mbs.2016.11.005por
dc.identifier.doi10.1016/j.mbs.2016.11.005-
degois.publication.volume283por
dc.date.embargo2018-12-21T14:35:45Z-
uc.controloAutoridadeSim-
item.fulltextCom Texto completo-
item.grantfulltextopen-
item.languageiso639-1en-
item.cerifentitytypePublications-
item.openairetypearticle-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
crisitem.author.deptFaculty of Sciences and Technology-
crisitem.author.deptFaculty of Sciences and Technology-
crisitem.author.parentdeptUniversity of Coimbra-
crisitem.author.parentdeptUniversity of Coimbra-
crisitem.author.researchunitCMUC - Centre for Mathematics of the University of Coimbra-
crisitem.author.researchunitCNC - Center for Neuroscience and Cell Biology-
crisitem.author.researchunitCMUC - Centre for Mathematics of the University of Coimbra-
crisitem.author.orcid0000-0002-5226-2905-
crisitem.author.orcid0000-0001-9255-3064-
crisitem.author.orcid0000-0001-6634-6651-
Appears in Collections:I&D CMUC - Artigos em Revistas Internacionais
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