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https://hdl.handle.net/10316/110214
Título: | Estradiol and progesterone regulate the migration of mast cells from the periphery to the uterus and induce their maturation and degranulation | Autor: | Jensen, Federico Woudwyk, Mariana Teles, Ana Woidacki, Katja Taran, Florin Costa, Serban Malfertheiner, Sara Fill Zenclussen, Ana Claudia |
Data: | 22-Dez-2010 | Editora: | Public Library of Science | Projeto: | Fritz-Thyssen Foundation (AZ. 10.08.2.179) German Research Foundation (DFG ZE 526/6-1 and SFB 854 TP7) German Research Foundation (DFG SPP 1394) |
Título da revista, periódico, livro ou evento: | PLoS ONE | Volume: | 5 | Número: | 12 | Resumo: | Mast cells (MCs) have long been suspected as important players for implantation based on the fact that their degranulation causes the release of pivotal factors, e.g., histamine, MMPs, tryptase and VEGF, which are known to be involved in the attachment and posterior invasion of the embryo into the uterus. Moreover, MC degranulation correlates with angiogenesis during pregnancy. The number of MCs in the uterus has been shown to fluctuate during menstrual cycle in human and estrus cycle in rat and mouse indicating a hormonal influence on their recruitment from the periphery to the uterus. However, the mechanisms behind MC migration to the uterus are still unknown. | URI: | https://hdl.handle.net/10316/110214 | ISSN: | 1932-6203 | DOI: | 10.1371/journal.pone.0014409 | Direitos: | openAccess |
Aparece nas coleções: | I&D IBILI - Artigos em Revistas Internacionais I&D CNC - Artigos em Revistas Internacionais |
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Estradiol-and-progesterone-regulate-the-migration-of-mast-cells-from-the-periphery-to-the-uterus-and-induce-their-maturation-and-degranulationPLoS-ONE.pdf | 1.96 MB | Adobe PDF | Ver/Abrir |
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