Lima, Maria C. Pedroso de

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Lima, Maria C. Pedroso de
 
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Lima, M. C. Pedroso de
 
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Lima, Maria C. Pedroso de
Lima, Maria Pedroso de
Lima, M. C. Pedroso de
 
 
 
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UC Researcher
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Publications

Results 1-83 of 83 (Search time: 0.002 seconds).

Issue DateTitleAuthor(s)TypeAccess
127-Jun-1997Actividade fusogénica de vírus com envelope lipídico : fusão de membranas promovida pelos vírus influenza e SendaiSantos, João Ramalho de Sousa doctoralThesisembargoedAccess
22008African swine fever virus p10 protein exhibits nuclear import capacity and accumulates in the nucleus during viral infectionNunes-Correia, Isabel ; Rodríguez, Javier M. ; Eulálio, Ana ; Carvalho, Ana L. ; Citovsky, Vitaly ; Simões, Sérgio ; Faro, Carlos ; Salas, María L. ; Lima, Maria C. Pedroso de articleopenAccess
32007African swine fever virus p37 structural protein is localized in nuclear foci containing the viral DNA at early post-infection timesEulálio, Ana ; Nunes-Correia, Isabel ; Salas, José ; Salas, Maria L. ; Simões, Sérgio ; Pedroso de Lima, Maria C. articleopenAccess
4Oct-2008Allele-specific RNA silencing of mutant ataxin-3 mediates neuroprotection in a rat model of Machado-Joseph diseaseAlves, Sandro ; Nascimento-Ferreira, Isabel ; Auregan, Gwennaëlle ; Hassig, Raymonde ; Dufour, Noëlle ; Brouillet, Emmanuel ; Lima, Maria C. Pedroso de ; Hantraye, Philippe ; Almeida, Luís Pereira de ; Déglon, Nicole articleopenAccess
52014Application of Thermoresponsive PNIPAAM‑b‑PAMPTMA Diblock Copolymers in siRNA DeliveryCardoso, Ana M. ; Calejo, M. Teresa ; Morais, Catarina M. ; Cardoso, Ana L. ; Cruz, Rita ; Zhu, Kaizheng ; Lima, M. C. P. de ; Jurado, A. S. ; Nyström, Bo articleopenAccess
62004Association of albumin or protamine to lipoplexes: enhancement of transfection and resistance to serumFaneca, H. ; Simões, S. ; Lima, M. C. Pedroso de articleopenAccess
72010Ataxin-3 aggregation and its impact on membrane destabilizationAlmeida, João Carlos Ribas de masterThesisopenAccess
82004Caveolae as an additional route for influenza virus endocytosis in MDCK cellsNunes-Correia, Isabel ; Eulálio, Ana ; Nir, Shlomo ; Lima, Maria C. Pedroso de articleopenAccess
930-Mar-2010Cell-Penetrating Peptides - Mechanisms of Cellular Uptake and Generation of Delivery SystemsTrabulo, Sara ; Cardoso, Ana Luísa ; Mano, Miguel ; Lima, Maria C. Pedroso de reviewopenAccess
1030-Mar-2010Cell-Penetrating Peptides-Mechanisms of Cellular Uptake and Generation of Delivery SystemsTrabulo, Sara ; Cardoso, Ana Luísa ; Mano, Miguel ; Lima, Maria C. Pedroso de articleopenAccess
111998Cholesterol affects African swine fever virus infectionBernardes, C. ; António, A. ; Pedroso de Lima, Maria C. ; Valdeira, M. L. articleopenAccess
12Mar-1993A common mechanism for influenza virus fusion activity and inactivationRamalho-Santos, João ; Nir, Shlomo ; Düzgünes, Nejat ; Carvalho, Arsélio Pato de ; Lima, Maria da Conceição Pedroso de articleopenAccess
1320-May-2004Cytotoxic Activity of Metal Complexes of Biogenic Polyamines: Polynuclear Platinum(II) ChelatesTeixeira, Luísa J. ; Seabra, Marta ; Reis, Elisa ; Cruz, M. Teresa Girão da ; Lima, M. Conceição Pedroso de ; Pereira, Eulália ; Miranda, M. Adelaide ; Marques, M. Paula M. articleopenAccess
142002Cytotoxic effects of metal complexes of biogenic polyamines. I. Platinum(II) spermidine compounds: prediction of their antitumour activityMarques, M. P. M. ; Girão, T. ; Lima, Maria C. Pedroso de ; Gameiro, A. ; Pereira, E. ; Garcia, P. articleopenAccess
1529-Jun-2010Desenvolvimento de novos sistemas baseados em lipossomas catiónicos para promover a entrega de material genético : caracterização físico-química e avaliação da actividade biológicasPereira, Nuno Miguel Penacho doctoralThesisembargoedAccess
162013Desenvolvimento de sistemas de base lipídica para a entrega de material genético em hepatocarcinomaMagalhães, Mariana Pereira masterThesisopenAccess
172011Desenvolvimento de um sistema de base lipidica para transporte e entrega de material genético a células de hepatocarcinomaFarinha, Dina Pereira Alves masterThesisopenAccess
182013Desenvolvimento de uma nova estratégia terapêutica para cancro da mama, envolvendo a acção combinada de terapia génica e quimioterapia.Santos, Gabriela de Jesus Leão Pereira dos masterThesisopenAccess
1925-Nov-2017Development of chitosan-based nanoparticles for nasal immunization against hepatitis BLebre, Filipa Raquel Maia Fontes doctoralThesisembargoedAccess (6 years)
202012Development of lipoplex formulations for specific genetic material delivery to pancreatic cancer cellsSaraiva, Claudia Marisa Monteiro masterThesisopenAccess
212012Development of liposomal formulations for drug delivery to breast cancer cellsRebelo, Catarina Araujo Gomes masterThesisopenAccess
22Jul-1987Electrical conductivity, viscosity, and density of a two-component ionic system at its critical pointSchreiber, Donald R. ; Lima, M. Conceicão P. de ; Pitzer, Kenneth S. articleopenAccess
232004Electrochemical sensing of the behaviour of oligonucleotide lipoplexes at charged interfacesPiedade, J. A. P. ; Mano, M. ; Lima, M. C. Pedroso de ; Oretskaya, T. S. ; Oliveira-Brett, A. M. articleopenAccess
242002Evaluation of lipid-based reagents to mediate intracellular gene deliveryFaneca, H. ; Simões, S. ; Lima, M. C. Pedroso de articleopenAccess
252007Evaluation of the antitumoral effect mediated by IL-12 and HSV-tk genes when delivered by a novel lipid-based systemFaneca, H. ; Cabrita, A. S. ; Simões, S. ; Lima, M. C. Pedroso de articleopenAccess
262002Fluorescent probes for monitoring virus fusion kinetics: comparative evaluation of reliabilityNunes-Correia, Isabel ; Eulálio, Ana ; Nir, Shlomo ; Düzgünes, Nejat ; Ramalho-Santos, João ; Lima, Maria C. Pedroso de articleopenAccess
272001Fusion and Infection of Influenza and Sendai Viruses as Modulated by Dextran Sulfate: A Comparative StudyRamalho-Santos, João ; Lima, Maria Pedroso de articleopenAccess
282000Human serum albumin enhances DNA transfection by lipoplexes and confers resistance to inhibition by serumSimões, Sérgio ; Slepushkin, Vladimir ; Pires, Pedro ; Gaspar, Rogério ; Pedroso de Lima, Maria C. ; Düzgünes, Nejat articleopenAccess
292013Impact of anti-PLK1 siRNA-containing F3-targeted liposomes on the viability of both cancer and endothelial cellsGomes-da-Silva, Lígia C. ; Ramalho, José S. ; Lima, M. C. P. de ; Simões, Sérgio ; Moreira, João N. articleopenAccess
302004Improving lipoplex-mediated gene transfer into C6 glioma cells and primary neuronsCruz, M. Teresa Girão da ; Simões, Sérgio ; Pedroso de Lima, Maria C. articleopenAccess
31Oct-2010In vitro modulation of Bcl-2 levels in small cell lung cancer cells: effects on cell viabilitySantos, A. O. ; Pereira, J. P.; Lima, M. C. Pedroso de ; Simões, S. ; Moreira, J. N. articleopenAccess
32Oct-2014Increased gene delivery efficiency and specificity of a lipid-based nanosystem incorporating a glycolipidMagalhães, Mariana ; Farinha, Dina ; Lima, Maria Conceição Pedroso de ; Faneca, Henrique articleopenAccess
3322-Dec-2015Inflammation in Alzheimer's disease: deregulation and modulation of miRNA expression in the mononuclear phagocyte systemGuedes, Joana Ribeiro doctoralThesisembargoedAccess
341998The influenza virus hemagglutinin: a model protein in the study of membrane fusionRamalho-Santos, João ; Pedroso de Lima, Maria C. articleopenAccess
351999Interaction of cationic liposomes and their DNA complexes with monocytic leukemia cellsPires, Pedro ; Simões, Sérgio ; Nir, Shlomo ; Gaspar, Rogério ; Düzgünes, Nejat ; Pedroso de Lima, Maria C. articleopenAccess
362007Interaction of S413-PV cell penetrating peptide with model membranes: relevance to peptide translocation across biological membranesMano, Miguel ; Henriques, Ana ; Paiva, Artur ; Prieto, Manuel ; Gavilanes, Francisco ; Simões, Sérgio ; Lima, Maria C. Pedroso De articleopenAccess
3719-Jan-1999Interactions of Influenza Virus with Cultured Cells: Detailed Kinetic Modeling of Binding and EndocytosisNunes-Correia, Isabel ; Ramalho-Santos, João ; Nir, Shlomo ; Lima, Maria C. Pedroso de articleopenAccess
382013Involvement of microRNA in microglia-mediated immune responseGuedes, J. ; Cardoso, A. L. C. ; Lima, M. C. Pedroso de articleopenAccess
391992Kinetic modeling of Sendai virus fusion with PC-12 cells. Effect of pH and temperature on fusion and viral inactivationLima, Maria da Conceição Pedroso de ; Ramalho-Santos, João ; Martins, Maria de Fátima ; Carvalho, Arsélio Pato de ; Bairos, Vasco ; Nir, Shlomo articleopenAccess
4010-Aug-2020Lysosomal Storage Disease-Associated Neuropathy: Targeting Stable Nucleic Acid Lipid Particle (SNALP)-Formulated siRNAs to the Brain as a Therapeutic ApproachCoutinho, Maria Francisca; Santos, Juliana Inês; Mendonça, Liliana ; Matos, Liliana; Prata, Maria João ; Jurado, Amália ; Lima, Maria C. Pedroso de ; Alves, SandraarticleopenAccess
412016MicroRNA deregulation and chemotaxis and phagocytosis impairment in Alzheimer's diseaseGuedes, Joana R. ; Santana, Isabel ; Cunha, Catarina ; Duro, Diana ; Almeida, Maria R. ; Cardoso, Ana M. ; Lima, Maria C. Pedroso de ; Cardoso, Ana L. articleopenAccess
422014MicroRNA modulation combined with sunitinib as a novel therapeutic strategy for pancreatic cancerPassadouro, Marta ; Lima, Maria C. Pedroso de ; Faneca, Henrique articleopenAccess
4330-Dec-2014MicroRNA modulation in combination with chemotherapeutic drugs as a novel therapeutic strategy for pancreatic cancerCaetano, Marta Daniela Passadouro doctoralThesisopenAccess
4430-Sep-2013MicroRNAs as Molecular Targets for Cancer Therapy: On the Modulation of MicroRNA ExpressionCosta, Pedro M. ; Lima, M. C. Pedroso de articleopenAccess
4525-Jul-2013MicroRNAs as molecular targets for non-viral gene therapy of glioblastoma: development of a lipid-based nanosystem for nucleic acid delivery to brain tumor cellsCosta, Pedro Miguel Coutinho da doctoralThesisopenAccess
462013MiRNA contribution to APP metabolism and Aβ production in Alzheimer’s disease: Identification of new miRNA-related SNPs in the 3’UTR of human APP and ApoE genesSilva, Ricardo Jorge Carreira da masterThesisopenAccess
472014MiRNAs expression profiling and modulation in Glioblastoma Stem CellsBranco, Rúben Miguel Gonçalves masterThesisopenAccess
48Feb-2006Nuclear export of African swine fever virus p37 protein occurs through two distinct pathways and is mediated by three independent signalsEulálio, Ana ; Nunes-Correia, Isabel ; Carvalho, Ana Luísa ; Faro, Carlos ; Citovsky, Vitaly ; Salas, José ; Salas, Maria L. ; Simões, Sérgio ; Lima, Maria C. Pedroso de articleopenAccess
4923-Dec-2014Nucleic Acid Delivery Systems: From Biophysics to Biological ActivityCardoso, Ana Maria Sequeira doctoralThesisopenAccess
501999O uso de lipossomas fusogénicos em terapia génica.Simões, Sérgio Paulo de Magalhães doctoralThesisembargoedAccess
512015On the development of a novel targeted miRNA-based therapy towards glioblastomaCunha, Pedro Miguel Pacheco de Jesus da masterThesisopenAccess
522004On the formulation of pH-sensitive liposomes with long circulation timesSimões, Sérgio ; Moreira, João Nuno ; Fonseca, Cristina ; Düzgünes, Nejat ; Pedroso de Lima, Maria C. articleopenAccess
532001On the mechanisms of internalization and intracellular delivery mediated by pH-sensitive liposomesSimões, Sérgio ; Slepushkin, Vladimir ; Düzgünes, Nejat ; Pedroso de Lima, Maria C. articleopenAccess
541-Sep-2005On the mechanisms of the internalization of S4(13)-PV cell-penetrating peptideMano, Miguel ; Teodósio, Cristina ; Paiva, Artur ; Simões, Sérgio ; Lima, Maria C. Pedroso de articleopenAccess
5517-Jan-2005Optimização de complexos lipossoma catiónico-ADN para transfecção de células neuronaisCruz, Maria Teresa Girão da doctoralThesisembargoedAccess
5627-Sep-1996Partial fusion activity of influenza virus toward liposomes and erythrocyte ghosts is distinct from viral inactivationRamalho-Santos, João ; Lima, Maria C. Pedroso de ; Nir, Shlomo articleopenAccess
5710-Feb-2006Péptidos permeantes como sistemas promissores para transporte de ácidos nucleicos : mecanismos de internalização celular e actividade biológica do péptido S413-PVMano, Miguel Luís Cunha doctoralThesisembargoedAccess
5813-Feb-2014Resveratrol-induced activation of the Sirt1/AMPK axis in human CD4 T cells triggers replicative stress and an ATR-dependent cell cycle arrestCraveiro, Marco Filipe Marques doctoralThesisopenAccess
5916-Mar-1999Role of a Transbilayer pH Gradient in the Membrane Fusion Activity of the Influenza Virus Hemagglutinin: Use of the R18 Assay to Monitor Membrane MergingRamalho-Santos, João ; Lima, Maria C. Pedroso de articleopenAccess
602013Role of miR-21 in the regulation of microglia immune response to gliomaCustódia, Carlos Manuel Tavares da masterThesisopenAccess
612015Role of miR-29b in the regulation of progranulin and dna methyltransferases 3A and 3B expression : therapeutic potential in glioblastomaCosta, Raquel Pinho masterThesisopenAccess
622013Role of PDG in the regulation of the intracellular pool of mmp-2 : mmp-2 contribution to SNALP internalization in glioma cellsSerani, Angelo masterThesisopenAccess
632004The role of target membrane sialic acid residues in the fusion activity of the influenza virus: the effect of two types of ganglioside on the kinetics of membrane mergingRamalho-Santos, João ; Lima, Maria C. Pedroso de articleopenAccess
642008S4 13 - PV cell penetrating peptide and cationic liposomes act synergistically to mediate intracellular delivery of plasmid DNATrabulo, Sara ; Mano, Miguel ; Faneca, Henrique ; Cardoso, Ana Luísa ; Duarte, Sónia ; Henriques, Ana ; Paiva, Artur ; Gomes, Paula ; Simões, Sérgio ; Lima, Maria C. Pedroso de articleopenAccess
65Mar-2012S4(13)-PV cell-penetrating peptide induces physical and morphological changes in membrane-mimetic lipid systems and cell membranes: Implications for cell internalizationCardoso, Ana M. S. ; Trabulo, Sara ; Cardoso, Ana L. ; Lorents, Annely ; Morais, Catarina M. ; Gomes, Paula ; Nunes, Cláudia ; Lúcio, Marlene ; Reis, Salette ; Padari, Kärt ; Pooga, Margus ; Lima, Maria C. Pedroso de ; Jurado, Amália S. articleopenAccess
66Mar-2016Safety profile of the intravenous administration of brain-targeted stable nucleic acid lipid particlesConceição, Mariana ; Mendonça, Liliana ; Nóbrega, Clévio; Gomes, Célia ; Costa, Pedro ; Hirai, Hirokazu; Moreira, João Nuno ; Lima, Maria C. Pedroso de ; Manjunath, N.; Almeida, Luís Pereira de articleopenAccess
671998Sendai Virus Fusion Activity as Modulated by Target Membrane ComponentsNunes-Correia, Isabel ; Ramalho-Santos, João ; Pedroso de Lima, Maria C. articleopenAccess
682008Simultaneous evaluation of viability and Bcl-2 in small-cell lung cancerSantos, A. ; Ribeiro, A. B. Sarmento ; Lima, M. C. Pedroso de ; Simões, S. ; Moreira, J. N. articleopenAccess
692007siRNA delivery by a transferrin-associated lipid-based vector: a non-viral strategy to mediate gene silencingCardoso, A. L. C. ; Simões, S. ; Almeida, L. P. de ; Pelisek, J. ; Culmsee, C. ; Wagner, E. ; Lima, M. C. Pedroso de articleopenAccess
7015-Jul-2008Striatal and nigral pathology in a lentiviral rat model of Machado-Joseph diseaseAlves, Sandro ; Régulier, Etienne ; Nascimento-Ferreira, Isabel ; Hassig, Raymonde ; Dufour, Noelle ; Koeppen, Arnulf ; Carvalho, Ana Luísa ; Simões, Sérgio ; Lima, Maria C. Pedroso de ; Brouillet, Emmanuel ; Gould, Veronica Colomer ; Déglon, Nicole ; Almeida, Luís Pereira de articleopenAccess
71Nov-2012Suicide gene therapy in cancer: Where do we stand now?Duarte, Sónia ; Carle, Georges ; Faneca, Henrique ; Lima, Maria C. Pedroso de ; Pierrefite-Carle, Valérie articleopenAccess
72Nov-2013Sustained Release of Naltrexone from Poly(N-Isopropylacrylamide) MicrogelsKjoniksen, A.L. ; Calejo, M. T. ; Zhu, K.Z. ; Cardoso, A. M .S. ; Lima, M.C.P. de ; Jurado, A.S. ; Nystrom, B. ; Sande, S.A. articleopenAccess
732008Synergistic antitumoral effect of vinblastine and HSV-Tk/GCV gene therapy mediated by albumin-associated cationic liposomesFaneca, H. ; Faustino, A. ; Lima, M. C. Pedroso de articleopenAccess
742005Targeting of sterically stabilised pH-sensitive liposomes to human T-leukaemia cellsFonseca, Cristina ; Moreira, João N. ; Ciudad, Carlos J. ; Pedroso de Lima, Maria C. ; Simões, Sérgio articleopenAccess
7510-Jul-2008Terapia génica para doenças vasculares : desenvolvimento de novos vectores para a entrega intracelular de genes de factores angiogénicosFilipe, Ana Cristina da Silva doctoralThesisopenAccess
762008Tf-lipoplexes for neuronal siRNA delivery: A promising system to mediate gene silencing in the CNSCardoso, A. L. C. ; Simões, S. ; Almeida, L. P. de ; Plesnila, N. ; Lima, M. C. Pedroso de ; Wagner, E. ; Culmsee, C. articleopenAccess
77Sep-2012Towards a siRNA-containing nanoparticle targeted to breast cancer cells and the tumor microenvironmentGomes-da-Silva, Lígia C. ; Santos, Adriana O. ; Bimbo, Luís M. ; Moura, Vera ; Ramalho, José S. ; Lima, Maria C. Pedroso de ; Simões, Sérgio ; Moreira, João N. articleopenAccess
782006Transfection of oral cancer cells mediated by transferrin-associated lipoplexes: Mechanisms of cell death induced by herpes simplex virus thymidine kinase/ganciclovir therapyNeves, Sílvia S. ; Sarmento-Ribeiro, Ana B. ; Simões, Sérgio P. ; Pedroso de Lima, Maria C. articleopenAccess
792008Transferrin-Associated Lipoplexes as Gene Delivery Systems: Relevance of Mode of Preparation and Biophysical PropertiesPenacho, Nuno ; Filipe, Ana ; Simões, Sérgio ; Lima, Maria C. Pedroso de articleopenAccess
8012-Jan-2006Transporte núcleo-citoplasmático de proteínas estruturais do vírus da peste suína africana : mecanismos e relevância virológica da proteína p37Eulálio, Ana Sofia Bregieiro doctoralThesisembargoedAccess
812013Tumor-targeted Chlorotoxin-coupled Nanoparticles for Nucleic Acid Delivery to Glioblastoma Cells: A Promising System for Glioblastoma TreatmentCosta, Pedro M. ; Cardoso, Ana L. ; Mendonça, Liliana S. ; Serani, Angelo ; Custódia, Carlos ; Conceição, Mariana ; Simões, Sérgio ; Moreira, João N. ; Almeida, Luis Pereira de ; Lima, M. C. P. de articleopenAccess
82Sep-2004Two African swine fever virus proteins derived from a common precursor exhibit different nucleocytoplasmic transport activitiesEulálio, A. ; Nunes-Correia, I. ; Carvalho, A. L. ; Faro, C. ; Citovsky, V. ; Simões, S. ; Lima, M. C. Pedroso de articleopenAccess
832004Voltammetric behaviour of oligonucleotide lipoplexes adsorbed onto glassy carbon electrodesPiedade, J. A. P. ; Mano, M. ; Lima, M. C. Pedroso de ; Oretskaya, T. S. ; Oliveira-Brett, A. M. articleopenAccess